Selected Publications

  1. Lenas P and Ikonomou L (2018) Developmental engineering: Design of clinically efficacious bioartificial tissues through developmental and systems biology. Sci China Life Sci 61(8): 978-981. DOI: 10.1007/s11427-017-9255-3
  2. Wagner DE, Turner L, Panoskaltsis-Mortari A, Weiss DJ, Ikonomou L (2018) Co-opting of ClinicalTrials.gov by patient-funded studies. Lancet Respir Med 6(8): 579-581. DOI: 10.1016/S2213-2600(18)30242-X
  3. Weiss DJ, Turner L, Levine AD, Ikonomou L (2017) Medical societies, patient education initiatives, public debate and marketing of unproven stem cell interventions. Cytotherapy 20(2): 165-168. DOI: 10.1016/j.jcyt.2017.10.002
  4. Serra M, Alysandratos KD, Hawkins F, McCauley KB, Jacob A, Choi J, Caballero IS, Vedaie M, Kurmann AA, Ikonomou L, Hollenberg AN, Shannon JM, Kotton DN (2017) Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification. Development 2017 144(21): 3879-3893. DOI: 10.1242/dev.150193
  5. Wilson A and Ikonomou L (2017). Development and Bioengineering of Lung Regeneration. In Organ Regeneration Based on Developmental Biology, T. Tsuji, ed. (Singapore: Springer Singapore), pp. 237-257. DOI: 10.1007/978-981-10-3768-9_13
  6. Ikonomou L, Panoskaltsis-Mortari A, Wagner DE, Freishtat RJ, Weiss DJ (2017) Unproven Stem Cell Treatments for Lung Disease-An Emerging Public Health Problem, Am J Respir Crit Care Med 195(7): P13-P14. DOI: 10.1164/rccm.1957P13
  7. Dame K, Cincotta S, Lang AH, Sanghrajka RM, Zhang L, Choi J, Kwok L, Wilson T, Kandula MM, Monti S, Hollenberg AM, Mehta P, Kotton DN, Ikonomou L (2017) Thyroid progenitors are robustly derived from embryonic stem cells through transient, developmental stage-specific overexpression of Nkx2-1, Stem Cell Rep 8: 216-225. DOI: 10.1016/j.stemcr.2016.12.024
  8. Ikonomou L, Freishtat RJ, Wagner DE, Panoskaltsis-Mortari A, Weiss DJ (2016) The global emergence of unregulated stem cell treatments for respiratory diseases: Professional societies need to act. Ann Am Thorac Soc 18: 1205-1207. DOI: 10.1513/AnnalsATS.201604-277ED
  9. Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean YC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, Hollenberg AN, Kotton DN (2015) Regeneration of thyroid function by directed differentiation of pluripotent stem cells, Cell Stem Cell 17: 527-542. DOI: 10.1016/j.stem.2015.09.004
  10. Ikonomou L and Kotton DN (2015) Derivation of endodermal progenitors from pluripotent stem cells. J Cell Physiol 230: 246-258. DOI: 1002/jcp.24771
  11. Longmire TA, Ikonomou L, Hawkins F, Christodoulou C, Cao Y, Jean YC, Kwok LW, Shen SS, Dowton AA, Serra M, Green MD, Snoeck HS, Ramirez MI, Kotton DN (2012) Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells, Cell Stem Cell 10: 398-411.DOI: 1016/j.stem.2012.01.019
  12. Ikonomou L, Hemnes AR, Bilousova G, Hamid R, Loyd JE, Hatzopoulos AK, Kotton DN, Majka SM, Austin ED (2011) Programmatic Change: Lung Disease Research in the Era of Induced Pluripotency, Am J Physiol Lung Cell Mol Physiol 301: L830-835. DOI: 1152/ajplung.00255.2011
  13. Ott HC, Clippinger B, Conrad C, Schuetz C, Pomerantseva I, Ikonomou L, Kotton D, Vacanti JP (2010) Regeneration and orthotopic transplantation of a bioartificial lung, Nat Med 16: 927-933. DOI: 10.1038/nm.2193
  14. Lenas P, Moreno A, Ikonomou L, Mayer J, Honda H, Novellino A, Pintor J (2008) The complementarity of the technical tools of tissue engineering and the concepts of artificial organs for the design of functional bioartificial tissues. Artif Organs 32: 742-746. DOI: 1111/j.1525-1594.2008.00599.x

 

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