Selected Publications

1. Weiss D.J., Turner L., Levine A.D., and Ikonomou L. (2017) Medical societies, patient education initiatives, public debate and marketing of unproven stem cell interventions. In Press. DOI:

2. Serra M, Alysandratos KD, Hawkins F, McCauley KB, Jacob A, Choi J, Caballero IS, Vedaie M, Kurmann AA, Ikonomou L, Hollenberg AN, Shannon JM and Kotton DN (2017) Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification. Development. 2017 144(21): 3879-3893. DOI: 10.1242/dev.150193.

3. Wilson A. and Ikonomou L. (2017). Development and Bioengineering of Lung Regeneration. In Organ Regeneration Based on Developmental Biology, T. Tsuji, ed. (Singapore: Springer Singapore), pp. 237-257.

4. Ikonomou L, Panoskaltsis-Mortari A, Wagner DE, Freishtat RJ, Weiss DJ (2017) Unproven Stem Cell Treatments for Lung Disease-An Emerging Public Health Problem, Am J Respir Crit Care Med 195(7): P13-P14. DOI: 10.1164/rccm.1957P13

5. Dame K, Cincotta S, Lang AH, Sanghrajka RM, Zhang L, Choi J, Kwok L, Wilson T, Kandula MM, Monti S, Hollenberg AM, Mehta P, Kotton DN, Ikonomou L (2017) Thyroid progenitors are robustly derived from embryonic stem cells through transient, developmental stage-specific overexpression of Nkx2-1, Stem Cell Rep 8: 216-225. DOI: 10.1016/j.stemcr.2016.12.024

6. Ikonomou L, Freishtat RJ, Wagner DE, Panoskaltsis-Mortari A, Weiss DJ (2016) The global emergence of unregulated stem cell treatments for respiratory diseases: Professional societies need to act. Ann. Am. Thorac. Soc. 18: 1205-1207. DOI: 10.1513/AnnalsATS.201604-277ED

7. Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean YC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, Hollenberg AN and Kotton DN (2015) Regeneration of thyroid function by directed differentiation of pluripotent stem cells, Cell Stem Cell 17: 527-542. DOI: 10.1016/j.stem.2015.09.004

8. Ikonomou L, Kotton DN (2015) Derivation of endodermal progenitors from pluripotent stem cells. J. Cell. Physiol. 230: 246-258. DOI: 1002/jcp.24771

9. Longmire TA, Ikonomou L, Hawkins F, Christodoulou C, Cao Y, Jean YC, Kwok LW, Shen SS, Dowton AA, Serra M, Green MD, Snoeck HS, Ramirez MI and Kotton DN (2012) Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells, Cell Stem Cell 10: 398-411.DOI: 1016/j.stem.2012.01.019

10. Ikonomou L, Hemnes AR, Bilousova G, Hamid R, Loyd JE, Hatzopoulos AK, Kotton DN, Majka SM and Austin ED (2011) Programmatic Change: Lung Disease Research in the Era of Induced Pluripotency, Am. J. Physiol. Lung Cell. Mol. Physiol. 301: L830-835. DOI: 1152/ajplung.00255.2011

11. Ott HC, Clippinger B, Conrad C, Schuetz C, Pomerantseva I, Ikonomou L, Kotton D and Vacanti JP (2010) Regeneration and orthotopic transplantation of a bioartificial lung, Nat. Med. 16: 927-933. DOI: 10.1038/nm.2193

12. Lenas P, Moreno A, Ikonomou L, Mayer J, Honda H, Novellino A and Pintor J (2008) The complementarity of the technical tools of tissue engineering and the concepts of artificial organs for the design of functional bioartificial tissues. Artif. Organs 32: 742-746. DOI: 1111/j.1525-1594.2008.00599.x


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